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Angela T S Wyse Selected Research

Adenosine Triphosphatases (ATPase)

11/2022Mild Hyperhomocysteinemia Causes Anxiety-like Behavior and Brain Hyperactivity in Rodents: Are ATPase and Excitotoxicity by NMDA Receptor Overstimulation Involved in this Effect?
1/2022Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model.
11/2019The neuroprotective role of melatonin in a gestational hypermethioninemia model.
11/2019Cross-talk between guanidinoacetate neurotoxicity, memory and possible neuroprotective role of creatine.
1/2018Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na+,K+-ATPase Expression/Content in Brain of Rat Offspring.
11/2016Mechanistic basis of hypermethioninemia.
4/2016Severe Hyperhomocysteinemia Decreases Respiratory Enzyme and Na(+)-K(+) ATPase Activities, and Leads to Mitochondrial Alterations in Rat Amygdala.
1/2016Cerebral Oedema, Blood-Brain Barrier Breakdown and the Decrease in Na(+),K(+)-ATPase Activity in the Cerebral Cortex and Hippocampus are Prevented by Dexamethasone in an Animal Model of Maple Syrup Urine Disease.
6/2014Oxidative stress mediated by NMDA, AMPA/KA channels in acute hippocampal slices: neuroprotective effect of resveratrol.
4/2014Evaluation of Na+, K+-ATPase activity in the brain of young rats after acute administration of fenproporex.
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Angela T S Wyse Research Topics

Disease

54Body Weight (Weight, Body)
05/2024 - 12/2002
32Hyperhomocysteinemia
05/2024 - 12/2002
23Homocystinuria
08/2015 - 04/2002
14Inflammation (Inflammations)
05/2024 - 06/2010
14Hypermethioninemia
08/2020 - 11/2005
11Memory Disorders (Memory Loss)
11/2019 - 11/2005
9Cognitive Dysfunction
01/2023 - 11/2005
9Guanidinoacetate methyltransferase deficiency
11/2019 - 06/2003
9Seizures (Absence Seizure)
01/2017 - 09/2006
9Hyperargininemia
09/2015 - 07/2002
7Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2022 - 12/2009
7Metabolic Diseases (Metabolic Disease)
03/2012 - 09/2002
6Neuroinflammatory Diseases
03/2024 - 08/2012
5Cardiovascular Diseases (Cardiovascular Disease)
05/2024 - 03/2011
5Neurodegenerative Diseases (Neurodegenerative Disease)
09/2023 - 08/2008
5Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 06/2010
5Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome)
05/2018 - 02/2004
5Intellectual Disability (Idiocy)
06/2010 - 04/2002
52-Hydroxyglutaricaciduria
09/2005 - 06/2003
4Galactosemias (Galactosemia)
09/2023 - 05/2016
4Sepsis (Septicemia)
01/2023 - 10/2017
4Epilepsy (Aura)
06/2014 - 06/2004
4Neurologic Manifestations (Neurological Manifestations)
02/2013 - 08/2005
4Glutaric Acidemia I
10/2007 - 05/2002
3Alzheimer Disease (Alzheimer's Disease)
09/2023 - 01/2018
3Infections
10/2022 - 01/2007
3Brain Injuries (Brain Injury)
04/2022 - 01/2016
3Asthma (Bronchial Asthma)
01/2022 - 12/2019
3Necrosis
01/2018 - 04/2016
3Mania (Manias)
03/2016 - 04/2009
3Lung Injury
12/2015 - 02/2013
3Decapitation
04/2014 - 03/2005
3Muscle Hypotonia (Hypotonia)
06/2010 - 03/2006
3Canavan Disease (Leukodystrophy, Spongiform)
06/2010 - 08/2007
3Short chain Acyl CoA dehydrogenase deficiency
03/2006 - 12/2002
2COVID-19
08/2023 - 10/2022
2Phenylketonurias (Phenylketonuria)
06/2021 - 04/2002

Drug/Important Bio-Agent (IBA)

42Adenosine Triphosphatases (ATPase)IBA
11/2022 - 04/2002
40HomocysteineIBA
05/2024 - 06/2002
29EnzymesIBA
09/2023 - 06/2002
28AntioxidantsIBA
01/2023 - 06/2003
16Methionine (L-Methionine)FDA Link
11/2019 - 06/2002
13Proteins (Proteins, Gene)FDA Link
01/2023 - 04/2010
13Proline (L-Proline)FDA Link
04/2021 - 04/2003
13CreatineIBA
11/2019 - 06/2004
12CatalaseIBA
12/2015 - 06/2003
11Thiobarbituric Acid Reactive SubstancesIBA
12/2015 - 06/2003
10AcetylcholinesteraseIBA
01/2022 - 06/2003
10CytokinesIBA
07/2021 - 06/2010
10AcidsIBA
03/2008 - 05/2002
9glycocyamineIBA
11/2019 - 06/2003
9Superoxide DismutaseIBA
12/2015 - 06/2003
8Folic Acid (Vitamin M)FDA LinkGeneric
12/2023 - 02/2006
8Glutamic Acid (Glutamate)FDA Link
11/2022 - 06/2007
8Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 11/2011
8NitritesIBA
01/2018 - 06/2010
8Saline SolutionIBA
10/2016 - 03/2003
8SolutionsIBA
10/2016 - 03/2003
7Methylphenidate (Ritalin)FDA LinkGeneric
01/2022 - 12/2009
7Amino AcidsFDA Link
06/2021 - 12/2003
7Creatine Kinase (Creatine Phosphokinase)IBA
01/2019 - 06/2003
7ButyrylcholinesteraseIBA
08/2015 - 09/2003
6Adenosine Triphosphate (ATP)IBA
03/2024 - 03/2006
6VitaminsIBA
12/2023 - 09/2002
5Cholinesterases (Cholinesterase)IBA
05/2024 - 09/2003
5Purinergic P2X7 ReceptorsIBA
03/2024 - 10/2017
5Glutathione PeroxidaseIBA
12/2015 - 06/2003
5Arginine (L-Arginine)FDA Link
10/2010 - 07/2002
5Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)IBA
09/2010 - 06/2003
4Galactose (Galactopyranose)FDA LinkGeneric
09/2023 - 05/2016
4SulfitesIBA
08/2023 - 03/2008
4Electron Transport Complex IV (Cytochrome c Oxidase)IBA
07/2021 - 04/2014
4Glucose (Dextrose)FDA LinkGeneric
11/2018 - 06/2006
4HypoxanthineIBA
05/2018 - 02/2004
4Succinate Dehydrogenase (Fumarate Reductase)IBA
01/2018 - 09/2002
4Sulfhydryl Compounds (Thiols)IBA
09/2015 - 06/2007
4Cystathionine beta-Synthase (Serine Sulfhydrase)IBA
07/2014 - 06/2003
3NucleotidesIBA
03/2024 - 03/2012
3Cholinergic Agents (Cholinergics)IBA
08/2023 - 03/2011
3Sulfite OxidaseIBA
08/2023 - 11/2016
3Glutathione (Reduced Glutathione)IBA
01/2023 - 07/2014
3Ascorbic Acid (Vitamin C)FDA LinkGeneric
01/2023 - 11/2005
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2022 - 05/2002
3Quinolinic AcidIBA
04/2022 - 10/2007
3Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2022 - 12/2011
3ResveratrolIBA
01/2019 - 10/2011
3Interleukin-6 (Interleukin 6)IBA
01/2018 - 12/2015
3Nerve Growth Factors (Neurotrophins)IBA
01/2018 - 12/2011
3Neuroprotective AgentsIBA
02/2016 - 10/2011
3LipopolysaccharidesIBA
12/2015 - 02/2013
3Oxygen (Dioxygen)IBA
04/2011 - 06/2003
3N-acetylaspartate (N-acetyl aspartate)IBA
06/2010 - 08/2007
2Purinergic Receptors (Receptors, Purine)IBA
03/2024 - 01/2019
2Central Nervous System StimulantsIBA
01/2022 - 12/2009
2Interleukin-10 (Interleukin 10)IBA
07/2021 - 12/2015
2Phenylalanine (L-Phenylalanine)FDA Link
06/2021 - 04/2002

Therapy/Procedure

32Subcutaneous Injections
11/2022 - 04/2003
6Therapeutics
01/2023 - 02/2008
4Ovariectomy (Oophorectomy)
09/2017 - 03/2005
3Ligation
01/2023 - 04/2011